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KMID : 0363220100480080725
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Korean Journal of Dermatology
2010 Volume.48 No. 8 p.725 ~ p.728
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Kikuchi`s Disease Presented with Cutaneous Lesion Showing Diffuse Erythematous Maculopatches
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Park Sang-Hoon
Noh Tae-Woo
Kang Yoo-Seok
Lee Un-Ha
Park Hyun-Su
Jang Sang-Jai
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Abstract
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Kikuchi’s disease, or histiocytic necrotizing lymphadenopathy is an idiopathic, benign self-limiting lymphadenitis usually affecting young women. Cutaneous findings in Kikuchi’s disease have been reported in 16∼40% of cases. A 29-year-old woman presented with pruritic diffuse erythematous maculopatches on whole body accompanied by long-lasting fever and cervical lymphadenopathy. Skin biopsy showed vacuolar degeneration of the basal layer and dermal infiltration of CD68-positive histiocytes. Lymph node fine needle aspiration specimens showed abundant lymphocytes, histiocytes, karyorrhectic debris without neutrophils, consistent with Kikuchi’s disease. We present a case of Kikuchi’s disease showing generalized skin eruption with a review of literature that describes patterns of skin involvement.
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KEYWORD
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Histiocytic necrotizing Lymphadenopathy, Kikuchi`s disease
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